Substance P è un gene codificato dal simbolo TAC1. È noto anche come: Protachykinin-1; PPT; TAC1; NKA; NKNA; TAC2. Substance P ha una massa di 15kDa e una lunghezza di amminoacidi di 129.
Offriamo 5 anticorpi contro Substance P, allevati nel Coniglio, Topo e Ratto, che sono adatti per WB, IHC, ELISA e ICC/IF con campioni derivati da Umano, Topo, Ratto, Bovino, Maiale, Coniglio, Pecora, Pollo, Porcellino d'India e Zebrafish.
Informazioni su geni e proteine
Riepilogo UniProt
Tachykinins are active peptides which excite neurons, evoke behavioral responses, are potent vasodilators and secretagogues, and contract (directly or indirectly) many smooth muscles.
Sommario di Entrez
This gene encodes four products of the tachykinin peptide hormone family, substance P and neurokinin A, as well as the related peptides, neuropeptide K and neuropeptide gamma. These hormones are thought to function as neurotransmitters which interact with nerve receptors and smooth muscle cells. They are known to induce behavioral responses and function as vasodilators and secretagogues. Substance P is an antimicrobial peptide with antibacterial and antifungal properties. Multiple transcript variants encoding different isoforms have been found for this gene.
Somiglianze di sequenza
Belongs to the tachykinin family.
Modifica post-translazionale
The substance P form is cleaved at Pro-59 by the prolyl endopeptidase FAP (seprase) activity (in vitro).
Posizione cellulare
Secreted.
