SPACA3 è un gene codificato dal simbolo SPACA3. È noto anche come: Sperm acrosome membrane-associated protein 3; Cancer/testis antigen 54; CT54; Lysozyme-like acrosomal sperm-specific secretory protein ALLP-17; Lysozyme-like protein 3; Sperm lysozyme-like protein 1; Sperm protein reactive with antisperm antibodies; Sperm protein reactive with ASA; LYC3; LYZL3; SLLP1; SPRASA. SPACA3 ha una massa di 23.43kDa e una lunghezza di amminoacidi di 215.
Offriamo 13 anticorpi contro SPACA3, allevati nel Coniglio, che sono adatti per WB, IHC, ELISA e IP con campioni derivati da Umano, Topo e Ratto.
Informazioni su geni e proteine
Riepilogo UniProt
Sperm surface membrane protein that may be involved in sperm-egg plasma membrane adhesion and fusion during fertilization. It could be a potential receptor for the egg oligosaccharide residue N-acetylglucosamine, which is present in the extracellular matrix over the egg plasma membrane. The processed form has no detectable bacteriolytic activity in vitro.
Sommario di Entrez
The protein encoded by this gene is a sperm surface protein that may be involved in adhesion to the egg prior to fertilization. While the encoded protein has significant similarity to lysozyme at the amino acid level, it has no detectable bacteriocidal activity. Several transcript variants encoding different isoforms have been found for this gene.
Specificità del tessuto
The processed form is expressed in sperm (at protein level). Expressed in testis, epididymis and placenta.
Somiglianze di sequenza
Belongs to the glycosyl hydrolase 22 family.
Modifica post-translazionale
The processed form derives from the membrane form by proteolytic processing.
Posizione cellulare
Cytoplasmic vesicle > Secretory vesicle > Acrosome membrane.
Anterior acrosome in non-capacitated spermatozoa and retained in the equatorial segment and in the luminal face of both the inner and outer acrosomal membranes following capacitation and the acrosome reaction.
