SOX4 è un gene codificato dal simbolo SOX4. È noto anche come Transcription factor SOX-4. SOX4 ha una massa di 47.26kDa e una lunghezza di amminoacidi di 474.
Offriamo 6 anticorpi contro SOX4, allevati nel Coniglio e Topo, che sono adatti per WB, IHC, ICC/IF, Citometria a Flusso e IP con campioni derivati da Umano e Topo.
Informazioni su geni e proteine
Riepilogo UniProt
Transcriptional activator that binds with high affinity to the T-cell enhancer motif 5'-AACAAAG-3' motif (By similarity). Required for IL17A-producing Vgamma2-positive gamma-delta T-cell maturation and development, via binding to regulator loci of RORC to modulate expression (By similarity).
Sommario di Entrez
This intronless gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins, such as syndecan binding protein (syntenin). The protein may function in the apoptosis pathway leading to cell death as well as to tumorigenesis and may mediate downstream effects of parathyroid hormone (PTH) and PTH-related protein (PTHrP) in bone development. The solution structure has been resolved for the HMG-box of a similar mouse protein.
Specificità del tessuto
Testis, brain, and heart.
Posizione cellulare
Nucleus.
