SNAP23 è un gene codificato dal simbolo SNAP23. È noto anche come: Synaptosomal-associated protein 23; SNAP-23; Vesicle-membrane fusion protein SNAP-23. SNAP23 ha una massa di 23.35kDa e una lunghezza di amminoacidi di 211.
Offriamo 6 anticorpi contro SNAP23, allevati nel Coniglio e Capra, che sono adatti per WB, IHC e ELISA con campioni derivati da Umano, Topo e Ratto.
Informazioni su geni e proteine
Riepilogo UniProt
Essential component of the high affinity receptor for the general membrane fusion machinery and an important regulator of transport vesicle docking and fusion.
Sommario di Entrez
Specificity of vesicular transport is regulated, in part, by the interaction of a vesicle-associated membrane protein termed synaptobrevin/VAMP with a target compartment membrane protein termed syntaxin. These proteins, together with SNAP25 (synaptosome-associated protein of 25 kDa), form a complex which serves as a binding site for the general membrane fusion machinery. Synaptobrevin/VAMP and syntaxin are believed to be involved in vesicular transport in most, if not all cells, while SNAP25 is present almost exclusively in the brain, suggesting that a ubiquitously expressed homolog of SNAP25 exists to facilitate transport vesicle/target membrane fusion in other tissues. The protein encoded by this gene is structurally and functionally similar to SNAP25 and binds tightly to multiple syntaxins and synaptobrevins/VAMPs. It is an essential component of the high affinity receptor for the general membrane fusion machinery and is an important regulator of transport vesicle docking and fusion. Two alternative transcript variants encoding different protein isoforms have been described for this gene.
Specificità del tessuto
Ubiquitous. Highest levels where found in placenta.
Somiglianze di sequenza
Belongs to the SNAP-25 family.
Posizione cellulare
Cell membrane. Cell membrane. Cell junction > Synapse > Synaptosome.
Mainly localized to the plasma membrane.
