SFRP2 è un gene codificato dal simbolo SFRP2. È noto anche come: Secreted frizzled-related protein 2; FRP-2; Secreted apoptosis-related protein 1; SARP-1; FRP2; SARP1. SFRP2 ha una massa di 33.49kDa e una lunghezza di amminoacidi di 295.
Offriamo 11 anticorpi contro SFRP2, allevati nel Coniglio e Capra, che sono adatti per WB, IHC, ELISA e ICC/IF con campioni derivati da Umano, Topo e Ratto.
Informazioni su geni e proteine
Riepilogo UniProt
Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP2 may be important for eye retinal development and for myogenesis.
Sommario di Entrez
This gene encodes a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. SFRPs act as soluble modulators of Wnt signaling. Methylation of this gene is a potential marker for the presence of colorectal cancer.
Specificità del tessuto
Expressed in adipose tissue, heart, brain, skeletal muscle, pancreas, thymus, prostate, testis, ovary, small intestine and colon. Highest levels in adipose tissue, small intestine and colon.
Somiglianze di sequenza
Belongs to the secreted frizzled-related protein (sFRP) family.
Posizione cellulare
Secreted.
