SCP2 è un gene codificato dal simbolo SYCP2. È noto anche come: Synaptonemal complex protein 2; SCP-2; Synaptonemal complex lateral element protein; hsSYCP2. SCP2 ha una massa di 175.64kDa e una lunghezza di amminoacidi di 1530.
Offriamo 5 anticorpi contro SCP2, allevati nel Coniglio, che sono adatti per WB, IHC e ICC/IF con campioni derivati da Umano, Topo e Ratto.
Informazioni su geni e proteine
Riepilogo UniProt
Major component of the axial/lateral elements of synaptonemal complexes (SCS) during meiotic prophase. Plays a role in the assembly of synaptonemal complexes. Required for normal meiotic chromosome synapsis during oocyte and spermatocyte development and for normal male and female fertility. Required for insertion of SYCP3 into synaptonemal complexes. May be involved in the organization of chromatin by temporarily binding to DNA scaffold attachment regions. Requires SYCP3, but not SYCP1, in order to be incorporated into the axial/lateral elements.
Sommario di Entrez
The synaptonemal complex is a proteinaceous structure that links homologous chromosomes during the prophase of meiosis. The protein encoded by this gene is a major component of the synaptonemal complex and may bind DNA at scaffold attachment regions. The encoded protein requires synaptonemal complex protein 3, but not 1, for inclusion in the synaptonemal complex.
Somiglianze di sequenza
Belongs to the SYCP2 family.
Modifica post-translazionale
Phosphorylated.
Posizione cellulare
Nucleus. Chromosome.
In axial/lateral elements of the tripartite segments of synaptonemal complexes.
