S100 calcium binding protein A14 è un gene codificato dal simbolo S100A14. È noto anche come: Protein S100-A14; S100 calcium-binding protein A14; S114; S100A14; S100A15. S100 calcium binding protein A14 ha una massa di 11.66kDa e una lunghezza di amminoacidi di 104.
Offriamo 10 anticorpi contro S100 calcium binding protein A14, allevati nel Coniglio e Topo, che sono adatti per WB, IHC, ELISA e ICC/IF con campioni derivati da Umano, Topo e Ratto.
Informazioni su geni e proteine
Riepilogo UniProt
Modulates P53/TP53 protein levels, and thereby plays a role in the regulation of cell survival and apoptosis. Depending on the context, it can promote cell proliferation or apoptosis. Plays a role in the regulation of cell migration by modulating the levels of MMP2, a matrix protease that is under transcriptional control of P53/TP53. Does not bind calcium.
Sommario di Entrez
This gene encodes a member of the S100 protein family which contains an EF-hand motif and binds calcium. The gene is located in a cluster of S100 genes on chromosome 1. Levels of the encoded protein have been found to be lower in cancerous tissue and associated with metastasis suggesting a tumor suppressor function (PMID: 19956863, 19351828).
Specificità del tessuto
Expressed at highest levels in colon and at moderate levels in thymus, kidney, liver, small intestine, and lung. Low expression in heart and no expression is seen in brain, skeletal muscle, spleen, placenta and peripheral blood leukocytes.
Somiglianze di sequenza
Belongs to the S-100 family.
Posizione cellulare
Cytoplasm.
