RPL3 è un gene codificato dal simbolo RPL3. È noto anche come: 60S ribosomal protein L3; HIV-1 TAR RNA-binding protein B; TARBP-B; Large ribosomal subunit protein uL3. RPL3 ha una massa di 46.11kDa e una lunghezza di amminoacidi di 403.
Offriamo 6 anticorpi contro RPL3, allevati nel Coniglio, che sono adatti per WB, IHC e ELISA con campioni derivati da Umano, Topo e Ratto.
Informazioni su geni e proteine
Riepilogo UniProt
The L3 protein is a component of the large subunit of cytoplasmic ribosomes.
Sommario di Entrez
Ribosomes, the complexes that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L3P family of ribosomal proteins and it is located in the cytoplasm. The protein can bind to the HIV-1 TAR mRNA, and it has been suggested that the protein contributes to tat-mediated transactivation. This gene is co-transcribed with several small nucleolar RNA genes, which are located in several of this gene's introns. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.
Somiglianze di sequenza
Belongs to the universal ribosomal protein uL3 family.
Posizione cellulare
Nucleus > Nucleolus. Cytoplasm.
