RhD è un gene codificato dal simbolo RHD. È noto anche come: Blood group Rh(D) polypeptide; RHXIII; Rh polypeptide 2; RhPII; Rhesus D antigen. RhD ha una massa di 45.21kDa e una lunghezza di amminoacidi di 417.
Offriamo 6 anticorpi contro RhD, allevati nel Coniglio e Human, che sono adatti per WB e ELISA con campioni derivati da Umano, Topo e Ratto.
Informazioni su geni e proteine
Riepilogo UniProt
May be part of an oligomeric complex which is likely to have a transport or channel function in the erythrocyte membrane.
Sommario di Entrez
The Rh blood group system is the second most clinically significant of the blood groups, second only to ABO. It is also the most polymorphic of the blood groups, with variations due to deletions, gene conversions, and missense mutations. The Rh blood group includes this gene, which encodes the RhD protein, and a second gene that encodes both the RhC and RhE antigens on a single polypeptide. The two genes, and a third unrelated gene, are found in a cluster on chromosome 1. The classification of Rh-positive and Rh-negative individuals is determined by the presence or absence of the highly immunogenic RhD protein on the surface of erythrocytes. Multiple transcript variants encoding different isoforms have been found for this gene.
Specificità del tessuto
Restricted to tissues or cell lines expressing erythroid characters.
Somiglianze di sequenza
Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily.
Modifica post-translazionale
Palmitoylated.
Posizione cellulare
Cell membrane.
