Retinoid X Receptor gamma è un gene codificato dal simbolo RXRG. È noto anche come: Retinoic acid receptor RXR-gamma; Nuclear receptor subfamily 2 group B member 3; RXRG; NR2B3. Retinoid X Receptor gamma ha una massa di 50.87kDa e una lunghezza di amminoacidi di 463.
Offriamo 7 anticorpi contro Retinoid X Receptor gamma, allevati nel Coniglio, Topo e Capra, che sono adatti per WB, IHC, ELISA, ICC/IF, Citometria a Flusso e IP con campioni derivati da Umano, Topo e Ratto.
Informazioni su geni e proteine
Riepilogo UniProt
Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RAR/RXR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. The high affinity ligand for RXRs is 9-cis retinoic acid (By similarity).
Sommario di Entrez
This gene encodes a member of the retinoid X receptor (RXR) family of nuclear receptors which are involved in mediating the antiproliferative effects of retinoic acid (RA). This receptor forms dimers with the retinoic acid, thyroid hormone, and vitamin D receptors, increasing both DNA binding and transcriptional function on their respective response elements. This gene is expressed at significantly lower levels in non-small cell lung cancer cells. Alternatively spliced transcript variants have been described.
Specificità del tessuto
Expressed in aortic endothelial cells (at protein level).
Somiglianze di sequenza
Belongs to the nuclear hormone receptor family. NR2 subfamily.
Modifica post-translazionale
Acetylated by EP300.
Posizione cellulare
Nucleus. Cytoplasm.
