RAP2C è un gene codificato dal simbolo RAP2C. È noto anche come Ras-related protein Rap-2c. RAP2C ha una massa di 20.75kDa e una lunghezza di amminoacidi di 183.
Offriamo 3 anticorpi contro RAP2C, allevati nel Coniglio, che sono adatti per WB, IHC e ELISA con campioni derivati da Umano e Topo.
Informazioni su geni e proteine
Riepilogo UniProt
Small GTP-binding protein which cycles between a GDP-bound inactive and a GTP-bound active form. May play a role in cytoskeletal rearrangements and regulate cell spreading through activation of the effector TNIK. May play a role in SRE-mediated gene transcription.
Sommario di Entrez
The protein encoded by this gene is a member of the Ras-related protein subfamily of the Ras GTPase superfamily. Members of this family are small GTPases that act as molecular switches to regulate cellular proliferation, differentiation, and apoptosis. This protein has been reported to activate in vitro transcriptional activity of the serum response element. Alternative splicing results in multiple transcript variants.
Specificità del tessuto
Expressed in liver, skeletal muscle, prostate, uterus, rectum, stomach, and bladder and to a lower extent in brain, kidney, pancreas, and bone marrow. Expressed in mononuclear leukocytes and megakaryocytes.
Somiglianze di sequenza
Belongs to the small GTPase superfamily. Ras family.
Modifica post-translazionale
Palmitoylated. Palmitoylation is required for association with recycling endosome membranes and activation of TNIK.
Posizione cellulare
Cytoplasm. Recycling endosome membrane.
