Rab4 è un gene codificato dal simbolo RAB4A. È noto anche come Ras-related protein Rab-4AA. Rab4 ha una massa di 24.39kDa e una lunghezza di amminoacidi di 218.
Offriamo 8 anticorpi contro Rab4, allevati nel Coniglio, Topo e Capra, che sono adatti per WB, IHC, ELISA e ICC/IF con campioni derivati da Umano, Topo, Ratto, Scimmia e Cane.
Informazioni su geni e proteine
Riepilogo UniProt
Protein transport. Plays a role in vesicular traffic. Mediates VEGFR2 endosomal trafficking to enhance VEGFR2 signaling.
Sommario di Entrez
This gene is a member of the largest group in the Ras superfamily of small GTPases, which regulate membrane trafficking. The encoded protein is associated with early endosomes and is involved in their sorting and recycling. The protein also plays a role in regulating the recycling of receptors from endosomes to the plasma membrane. Alternatively spliced transcript variants have been observed for this gene.
Somiglianze di sequenza
Belongs to the small GTPase superfamily. Rab family.
Modifica post-translazionale
Phosphorylated by CDK1 kinase during mitosis.
Posizione cellulare
Membrane. Cytoplasm. Early endosome membrane. Recycling endosome membrane.
Generally associated with membranes. Cytoplasmic when phosphorylated by CDK1.
