Rab2 è un gene codificato dal simbolo RAB2A. È noto anche come Ras-related protein Rab-2AA. Rab2 ha una massa di 23.55kDa e una lunghezza di amminoacidi di 212.
Offriamo 9 anticorpi contro Rab2, allevati nel Coniglio, Topo e Capra, che sono adatti per WB, IHC, ELISA e ICC/IF con campioni derivati da Umano, Topo, Ratto, Scimmia e Cane.
Informazioni su geni e proteine
Riepilogo UniProt
Required for protein transport from the endoplasmic reticulum to the Golgi complex.
Sommario di Entrez
The protein encoded by this gene belongs to the Rab family, members of which are small molecular weight guanosine triphosphatases (GTPases) that contain highly conserved domains involved in GTP binding and hydrolysis. The Rabs are membrane-bound proteins, involved in vesicular fusion and trafficking. This protein is a resident of pre-Golgi intermediates, and is required for protein transport from the endoplasmic reticulum (ER) to the Golgi complex. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Somiglianze di sequenza
Belongs to the small GTPase superfamily. Rab family.
Posizione cellulare
Endoplasmic reticulum-Golgi intermediate compartment membrane. Melanosome. Endoplasmic reticulum membrane. Golgi apparatus membrane.
Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
