Phospholipase A2 IID è un gene codificato dal simbolo PLA2G2D. Comunemente indicato anche come: Group IID secretory phospholipase A2; GIID sPLA2; PLA2IID; Phosphatidylcholine 2-acylhydrolase 2D; Secretory-type PLA, stroma-associated homolog; PLA2G2D; SPLASH. Phospholipase A2 IID ha una massa di 16.55kDa e una lunghezza di amminoacidi di 145.
Offriamo 3 anticorpi contro Phospholipase A2 IID, allevati nel Coniglio, che sono adatti per WB, IHC e ICC/IF con campioni derivati da Umano e Ratto.
Informazioni su geni e proteine
Riepilogo UniProt
PA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides. L-alpha-1-palmitoyl-2-linoleoyl phosphatidylethanolamine is more efficiently hydrolyzed than the other phospholipids examined.
Sommario di Entrez
This gene encodes a secreted member of the phospholipase A2 family, and is found in a cluster of related family members on chromosome 1. Phospholipase A2 family members hydrolyze the sn-2 fatty acid ester bond of glycerophospholipids to produce lysophospholipids and free fatty acid. This gene may be involved in inflammation and immune response, and in weight loss associated with chronic obstructive pulmonary disease. Alternative splicing results in multiple transcript variants encoding different isoforms.
Specificità del tessuto
Broadly expressed.
Somiglianze di sequenza
Belongs to the phospholipase A2 family.
Posizione cellulare
Secreted.
