PGD è un gene codificato dal simbolo PGD. È noto anche come 6-phosphogluconate dehydrogenase, decarboxylatingH. PGD ha una massa di 53.14kDa e una lunghezza di amminoacidi di 483.
Offriamo 6 anticorpi contro PGD, allevati nel Coniglio e Topo, che sono adatti per WB, IHC, ELISA, ICC/IF, Citometria a Flusso e IP con campioni derivati da Umano, Topo e Ratto.
Informazioni su geni e proteine
Riepilogo UniProt
Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
Sommario di Entrez
6-phosphogluconate dehydrogenase is the second dehydrogenase in the pentose phosphate shunt. Deficiency of this enzyme is generally asymptomatic, and the inheritance of this disorder is autosomal dominant. Hemolysis results from combined deficiency of 6-phosphogluconate dehydrogenase and 6-phosphogluconolactonase suggesting a synergism of the two enzymopathies. Several transcript variants encoding different isoforms have been found for this gene.
Somiglianze di sequenza
Belongs to the 6-phosphogluconate dehydrogenase family.
Posizione cellulare
Cytoplasm.
