Perilipin 3 è un gene codificato dal simbolo PLIN3. Comunemente indicato anche come: Perilipin-3; 47 kDa mannose 6-phosphate receptor-binding protein; 47 kDa MPR-binding protein; Cargo selection protein TIP47; Mannose-6-phosphate receptor-binding protein 1; Placental protein 17; PP17; PLIN3; M6PRBP1; TIP47. Perilipin 3 ha una massa di 47.08kDa e una lunghezza di amminoacidi di 434.
Offriamo 5 anticorpi contro Perilipin 3, allevati nel Coniglio e Capra, che sono adatti per WB, IHC, ELISA e ICC/IF con campioni derivati da Umano, Topo e Ratto.
Informazioni su geni e proteine
Riepilogo UniProt
Required for the transport of mannose 6-phosphate receptors (MPR) from endosomes to the trans-Golgi network.
Sommario di Entrez
Mannose 6-phophate receptors (MPRs) deliver lysosomal hydrolase from the Golgi to endosomes and then return to the Golgi complex. The protein encoded by this gene interacts with the cytoplasmic domains of both cation-independent and cation-dependent MPRs, and is required for endosome-to-Golgi transport. This protein also binds directly to the GTPase RAB9 (RAB9A), a member of the RAS oncogene family. The interaction with RAB9 has been shown to increase the affinity of this protein for its cargo. Multiple transcript variants encoding different isoforms have been found for this gene.
Somiglianze di sequenza
Belongs to the perilipin family.
Posizione cellulare
Cytoplasm. Endosome membrane. Lipid droplet.
Membrane associated on endosomes. Detected in the envelope and the core of lipid bodies and in lipid sails.
