PDE1A è un gene codificato dal simbolo PDE1A. Comunemente indicato anche come: Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A; Cam-PDE 1A; 61 kDa Cam-PDE; hCam-1. PDE1A ha una massa di 61.25kDa e una lunghezza di amminoacidi di 535.
Offriamo 10 anticorpi contro PDE1A, allevati nel Coniglio e Capra, che sono adatti per WB, IHC, ELISA, ICC/IF e IP con campioni derivati da Umano, Topo e Ratto.
Informazioni su geni e proteine
Riepilogo UniProt
Cyclic nucleotide phosphodiesterase with a dual-specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes. Has a higher affinity for cGMP than for cAMP.
Sommario di Entrez
Cyclic nucleotide phosphodiesterases (PDEs) play a role in signal transduction by regulating intracellular cyclic nucleotide concentrations through hydrolysis of cAMP and/or cGMP to their respective nucleoside 5-prime monophosphates. Members of the PDE1 family, such as PDE1A, are Ca(2+)/calmodulin (see CALM1; MIM 114180)-dependent PDEs (CaM-PDEs) that are activated by calmodulin in the presence of Ca(2+) (Michibata et al., 2001
Specificità del tessuto
Several tissues, including brain, kidney, testes and heart.
Somiglianze di sequenza
Belongs to the cyclic nucleotide phosphodiesterase family. PDE1 subfamily.
