P2Y4 è un gene codificato dal simbolo P2RY4. Comunemente indicato anche come: P2Y purinoceptor 4; P2P; Uridine nucleotide receptor; UNR; P2RY4; NRU. P2Y4 ha una massa di 40.96kDa e una lunghezza di amminoacidi di 365.
Offriamo 7 anticorpi contro P2Y4, allevati nel Coniglio, che sono adatti per WB, IHC, ELISA e ICC/IF con campioni derivati da Umano, Topo e Ratto.
Informazioni su geni e proteine
Riepilogo UniProt
Receptor for UTP and UDP coupled to G-proteins that activate a phosphatidylinositol-calcium second messenger system. Not activated by ATP or ADP.
Sommario di Entrez
The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is responsive to uridine nucleotides, partially responsive to ATP, and not responsive to ADP.
Specificità del tessuto
Pancreas.
Somiglianze di sequenza
Belongs to the G-protein coupled receptor 1 family.
Modifica post-translazionale
Phosphorylation of Ser-333 and Ser-334 is a key step in agonist-dependent desensitization and loss of surface P2RY4. This phosphorylation does not involve PKC, nor other calcium activated kinases.
Posizione cellulare
Cell membrane.
