OTUB2 è un gene codificato dal simbolo OTUB2. Comunemente indicato anche come: Ubiquitin thioesterase Deubiquitinating enzyme OTU domain-containing ubiquitin aldehyde-binding protein 2; Otubain-2; Ubiquitin-specific-processing protease C14orf137; OTB2; OTU2. OTUB2 ha una massa di 27.21kDa e una lunghezza di amminoacidi di 234.
Offriamo 6 anticorpi contro OTUB2, allevati nel Coniglio, Topo e Capra, che sono adatti per WB, IHC e ELISA con campioni derivati da Umano, Topo e Ratto.
Informazioni su geni e proteine
Riepilogo UniProt
Hydrolase that can remove conjugated ubiquitin from proteins in vitro and may therefore play an important regulatory role at the level of protein turnover by preventing degradation. Mediates deubiquitination of 'Lys-11'-,'Lys-48'- and 'Lys-63'-linked polyubiquitin chains, with a preference for 'Lys-63'-linked polyubiquitin chains.
Sommario di Entrez
This gene encodes one of several deubiquitylating enzymes. Ubiquitin modification of proteins is needed for their stability and function; to reverse the process, deubiquityling enzymes remove ubiquitin. This protein contains an OTU domain and binds Ubal (ubiquitin aldehyde); an active cysteine protease site is present in the OTU domain.
Specificità del tessuto
Widely expressed. Expressed at higher level in brain.
Somiglianze di sequenza
Belongs to the peptidase C65 family.
