Nkx2.2 è un gene codificato dal simbolo NKX2-2. Comunemente indicato anche come: Homeobox protein Nkx-2.2; Homeobox protein NK-2 homolog B; NKX2-2; NKX2B. Nkx2.2 ha una massa di 30.13kDa e una lunghezza di amminoacidi di 273.
Offriamo 27 anticorpi contro Nkx2.2, allevati nel Coniglio e Topo, che sono adatti per WB, IHC, ELISA, ICC/IF, Citometria a Flusso e IP con campioni derivati da Umano, Topo, Ratto e Pollo.
Informazioni su geni e proteine
Riepilogo UniProt
Transcriptional activator involved in the development of insulin-producting beta cells in the endocrine pancreas (By similarity). May also be involved in specifying diencephalic neuromeric boundaries, and in controlling the expression of genes that play a role in axonal guidance. Binds to elements within the NEUROD1 promoter (By similarity).
Sommario di Entrez
The protein encoded by this gene contains a homeobox domain and may be involved in the morphogenesis of the central nervous system. This gene is found on chromosome 20 near NKX2-4, and these two genes appear to be duplicated on chromosome 14 in the form of TITF1 and NKX2-8. The encoded protein is likely to be a nuclear transcription factor.
Somiglianze di sequenza
Belongs to the NK-2 homeobox family.
Posizione cellulare
Nucleus.
