MyoD1 è un gene codificato dal simbolo MYOD1. Comunemente indicato anche come: Myoblast determination protein 1; Class C basic helix-loop-helix protein 1; bHLHc1; Myogenic factor 3; Myf-3; BHLHC1; MYF3; MYOD. MyoD1 ha una massa di 34.5kDa e una lunghezza di amminoacidi di 320.
Offriamo 32 anticorpi contro MyoD1, allevati nel Coniglio e Topo, che sono adatti per WB, IHC, ELISA, ICC/IF e Citometria a Flusso con campioni derivati da Umano, Topo, Ratto e Pollo.
Informazioni su geni e proteine
Riepilogo UniProt
Acts as a transcriptional activator that promotes transcription of muscle-specific target genes and plays a role in muscle differentiation. Together with MYF5 and MYOG, co-occupies muscle-specific gene promoter core region during myogenesis. Induces fibroblasts to differentiate into myoblasts. Interacts with and is inhibited by the twist protein. This interaction probably involves the basic domains of both proteins (By similarity).
Sommario di Entrez
This gene encodes a nuclear protein that belongs to the basic helix-loop-helix family of transcription factors and the myogenic factors subfamily. It regulates muscle cell differentiation by inducing cell cycle arrest, a prerequisite for myogenic initiation. The protein is also involved in muscle regeneration. It activates its own transcription which may stabilize commitment to myogenesis.
Modifica post-translazionale
Phosphorylated by CDK9. This phosphorylation promotes its function in muscle differentiation.
Posizione cellulare
Nucleus.
