Muscarinic Acetylcholine Receptor 1 è un gene codificato dal simbolo CHRM1. Comunemente indicato anche come: Muscarinic acetylcholine receptor M1; CHRM1. Muscarinic Acetylcholine Receptor 1 ha una massa di 51.42kDa e una lunghezza di amminoacidi di 460.
Offriamo 6 anticorpi contro Muscarinic Acetylcholine Receptor 1, allevati nel Coniglio e Capra, che sono adatti per WB, IHC, ELISA e ICC/IF con campioni derivati da Umano, Topo e Ratto.
Informazioni su geni e proteine
Riepilogo UniProt
The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is Pi turnover.
Sommario di Entrez
The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The muscarinic cholinergic receptor 1 is involved in mediation of vagally-induced bronchoconstriction and in the acid secretion of the gastrointestinal tract. The gene encoding this receptor is localized to 11q13.
Somiglianze di sequenza
Belongs to the G-protein coupled receptor 1 family. Muscarinic acetylcholine receptor subfamily. CHRM1 sub-subfamily.
Posizione cellulare
Cell membrane. Cell junction > Synapse > Postsynaptic cell membrane.
