Anticorpi MRC2

6 prodotti

MRC2 è un gene codificato dal simbolo MRC2. Comunemente indicato anche come: C-type mannose receptor 2; C-type lectin domain family 13 member E; Endocytic receptor 180; Macrophage mannose receptor 2; Urokinase-type plasminogen activator receptor-associated protein; UPAR-associated protein; CLEC13E; ENDO180; KIAA0709; UPARAP. MRC2 ha una massa di 166.67kDa e una lunghezza di amminoacidi di 1479.

Offriamo 6 anticorpi contro MRC2, allevati nel Coniglio, che sono adatti per WB, IHC, ELISA e ICC/IF con campioni derivati ​​da Umano, Topo e Ratto.

Informazioni su geni e proteine

Riepilogo UniProt
May play a role as endocytotic lectin receptor displaying calcium-dependent lectin activity. Internalizes glycosylated ligands from the extracellular space for release in an endosomal compartment via clathrin-mediated endocytosis. May be involved in plasminogen activation system controlling the extracellular level of PLAUR/PLAU, and thus may regulate protease activity at the cell surface. May contribute to cellular uptake, remodeling and degradation of extracellular collagen matrices. May play a role during cancer progression as well as in other chronic tissue destructive diseases acting on collagen turnover. May participate in remodeling of extracellular matrix cooperating with the matrix metalloproteinases (MMPs).
Sommario di Entrez
This gene encodes a member of the mannose receptor family of proteins that contain a fibronectin type II domain and multiple C-type lectin-like domains. The encoded protein plays a role in extracellular matrix remodeling by mediating the internalization and lysosomal degradation of collagen ligands. Expression of this gene may play a role in the tumorigenesis and metastasis of several malignancies including breast cancer, gliomas and metastatic bone disease.
Specificità del tessuto
Ubiquitous with low expression in brain, placenta, lung, kidney, pancreas, spleen, thymus and colon. Expressed in endothelial cells, fibroblasts and macrophages. Highly expressed in fetal lung and kidney.
Modifica post-translazionale
N-glycosylated.
Posizione cellulare
Membrane.
Western Blot - Anti-MRC2 Antibody (C11813) - Antibodies.com
(4)
Visualizza prodotto10µg Dimensione di prova
Western Blot - Anti-MRC2 Antibody (C30509) - Antibodies.com
(4)
Visualizza prodotto10µg Dimensione di prova
Western blot - MRC2 Antibody from Signalway Antibody (34093) - Antibodies.com
(3)
Western blot - Endo180 Polyclonal Antibody from Signalway Antibody (40881) - Antibodies.com
Anti-Endo180 (G145) Antibody from Bioworld Technology (BS2506) - Antibodies.com
(2)
Western blot - Endo180 Polyclonal Antibody from Signalway Antibody (41788) - Antibodies.com

Mostra 1-6 di 6 prodotti

Filtri Menù Principale Contattaci 0Check-out
Inizio pagina