MMP10 è un gene codificato dal simbolo MMP10. Comunemente indicato anche come: Stromelysin-2; SL-2; Matrix metalloproteinase-10; MMP-10; Transin-2; STMY2. MMP10 ha una massa di 54.15kDa e una lunghezza di amminoacidi di 476.
Offriamo 10 anticorpi contro MMP10, allevati nel Coniglio, che sono adatti per WB, IHC, ELISA e ICC/IF con campioni derivati da Umano, Topo e Ratto.
Informazioni su geni e proteine
Riepilogo UniProt
Can degrade fibronectin, gelatins of type I, III, IV, and V; weakly collagens III, IV, and V. Activates procollagenase.
Sommario di Entrez
This gene encodes a member of the peptidase M10 family of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded preproprotein is proteolytically processed to generate the mature protease. This secreted protease breaks down fibronectin, laminin, elastin, proteoglycan core protein, gelatins, and several types of collagen. The gene is part of a cluster of MMP genes on chromosome 11.
Somiglianze di sequenza
Belongs to the peptidase M10A family.
Posizione cellulare
Secreted > Extracellular space > Extracellular matrix.
