MEF2B è un gene codificato dal simbolo MEF2B. Comunemente indicato anche come: Myocyte-specific enhancer factor 2B; RSRFR2; Serum response factor-like protein 2; XMEF2. MEF2B ha una massa di 38.64kDa e una lunghezza di amminoacidi di 365.
Offriamo 6 anticorpi contro MEF2B, allevati nel Coniglio e Topo, che sono adatti per WB, ELISA, ICC/IF, Citometria a Flusso e IP con campioni derivati da Umano e Topo.
Informazioni su geni e proteine
Riepilogo UniProt
Transcriptional activator which binds specifically to the MEF2 element, 5'-YTA[AT](4)TAR-3', found in numerous muscle-specific genes. Activates transcription via this element. May be involved in muscle-specific and/or growth factor-related transcription.
Sommario di Entrez
The product of this gene is a member of the MADS/MEF2 family of DNA binding proteins. The protein is thought to regulate gene expression, including expression of the smooth muscle myosin heavy chain gene. This region undergoes considerable alternative splicing, with transcripts supporting two non-overlapping loci (GeneID 729991 and 100271849) as well as numerous read-through transcripts that span both loci (annotated as GeneID 4207). Several isoforms of this protein are expressed from either this locus or from some of the read-through transcripts annotated on GeneID 4207.
Specificità del tessuto
Expressed in skeletal and cardiac muscle and brain.
Somiglianze di sequenza
Belongs to the MEF2 family.
Posizione cellulare
Nucleus.
