MC4 Receptor è un gene codificato dal simbolo MC4R. Comunemente indicato anche come: Melanocortin receptor 4; MC4-R; MC4R. MC4 Receptor ha una massa di 36.94kDa, una lunghezza di amminoacidi di 332, ed è implicato in Obesity.
Offriamo 9 anticorpi contro MC4 Receptor, allevati nel Coniglio, che sono adatti per WB, IHC, ELISA e IP con campioni derivati da Umano, Topo e Ratto.
Informazioni su geni e proteine
Riepilogo UniProt
Receptor specific to the heptapeptide core common to adrenocorticotropic hormone and alpha-, beta-, and gamma-MSH. Plays a central role in energy homeostasis and somatic growth. This receptor is mediated by G proteins that stimulate adenylate cyclase (cAMP).
Sommario di Entrez
The protein encoded by this gene is a membrane-bound receptor and member of the melanocortin receptor family. The encoded protein interacts with adrenocorticotropic and MSH hormones and is mediated by G proteins. This is an intronless gene. Defects in this gene are a cause of autosomal dominant obesity.
Specificità del tessuto
Brain, placental, and gut tissues.
Coinvolgimento nella malattia
Obesity: A condition characterized by an increase of body weight beyond the limitation of skeletal and physical requirements, as the result of excessive accumulation of body fat.
Somiglianze di sequenza
Belongs to the G-protein coupled receptor 1 family.
Posizione cellulare
Cell membrane.
