Mannose Receptor è un gene codificato dal simbolo MRC1. Comunemente indicato anche come: Macrophage mannose receptor 1; MMR; C-type lectin domain family 13 member D; C-type lectin domain family 13 member D-like; Human hMR; Macrophage mannose receptor 1-like protein 1; MRC1; CLEC13D; CLEC13DL; MRC1L1. Mannose Receptor ha una massa di 166.01kDa e una lunghezza di amminoacidi di 1456.
Offriamo 18 anticorpi contro Mannose Receptor, allevati nel Coniglio, Topo e Ratto, che sono adatti per WB, IHC, ELISA, ICC/IF, Citometria a Flusso e IP con campioni derivati da Umano, Topo e Ratto.
Informazioni su geni e proteine
Riepilogo UniProt
Mediates the endocytosis of glycoproteins by macrophages. Binds both sulfated and non-sulfated polysaccharide chains.
Sommario di Entrez
The recognition of complex carbohydrate structures on glycoproteins is an important part of several biological processes, including cell-cell recognition, serum glycoprotein turnover, and neutralization of pathogens. The protein encoded by this gene is a type I membrane receptor that mediates the endocytosis of glycoproteins by macrophages. The protein has been shown to bind high-mannose structures on the surface of potentially pathogenic viruses, bacteria, and fungi so that they can be neutralized by phagocytic engulfment.
Posizione cellulare
Endosome membrane. Cell membrane.
