KIF20A è un gene codificato dal simbolo KIF20A. Comunemente indicato anche come: Kinesin-like protein GG10_2; Mitotic kinesin-like protein 2; MKlp2; Rab6-interacting kinesin-like protein; Rabkinesin-6; MKLP2; RAB6KIFL. KIF20A ha una massa di 100.28kDa e una lunghezza di amminoacidi di 890.
Offriamo 8 anticorpi contro KIF20A, allevati nel Coniglio, che sono adatti per WB, IHC, ELISA e ICC/IF con campioni derivati da Umano, Topo e Ratto.
Informazioni su geni e proteine
Riepilogo UniProt
Mitotic kinesin required for chromosome passenger complex (CPC)-mediated cytokinesis. Following phosphorylation by PLK1, involved in recruitment of PLK1 to the central spindle. Interacts with guanosine triphosphate (GTP)-bound forms of RAB6A and RAB6B. May act as a motor required for the retrograde RAB6 regulated transport of Golgi membranes and associated vesicles along microtubules. Has a microtubule plus end-directed motility.
Somiglianze di sequenza
Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
Modifica post-translazionale
Phosphorylated by PLK1 at Ser-528 during mitosis, creating a docking site for PLK1 and recruiting PLK1 at central spindle.
Posizione cellulare
Golgi apparatus. Cytoplasm > Cytoskeleton > Spindle.
