Kallikrein 5 è un gene codificato dal simbolo KLK5. Comunemente indicato anche come: Kallikrein-5; Kallikrein-like protein 2; KLK-L2; Stratum corneum tryptic enzyme; KLK5; SCTE. Kallikrein 5 ha una massa di 32.02kDa e una lunghezza di amminoacidi di 293.
Offriamo 23 anticorpi contro Kallikrein 5, allevati nel Coniglio, Topo, Capra e Human, che sono adatti per WB, IHC e ELISA con campioni derivati da Umano, Topo e Ratto.
Informazioni su geni e proteine
Riepilogo UniProt
May be involved in desquamation.
Sommario di Entrez
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its expression is up-regulated by estrogens and progestins. The encoded protein is secreted and may be involved in desquamation in the epidermis. Alternative splicing results in multiple transcript variants encoding the same protein.
Specificità del tessuto
Expressed in skin, breast, brain and testis. Expressed at the stratum granulosum of palmar skin.
Somiglianze di sequenza
Belongs to the peptidase S1 family. Kallikrein subfamily.
Posizione cellulare
Secreted.
