IL9R è un gene codificato dal simbolo IL9R. Comunemente indicato anche come: Interleukin-9 receptor; IL-9 receptor. IL9R ha una massa di 57.15kDa e una lunghezza di amminoacidi di 521.
Offriamo 10 anticorpi contro IL9R, allevati nel Coniglio e Topo, che sono adatti per WB, IHC, ELISA, ICC/IF e Citometria a Flusso con campioni derivati da Umano, Topo e Ratto.
Informazioni su geni e proteine
Riepilogo UniProt
This is a receptor for interleukin-9.
Sommario di Entrez
The protein encoded by this gene is a cytokine receptor that specifically mediates the biological effects of interleukin 9 (IL9). The functional IL9 receptor complex requires this protein as well as the interleukin 2 receptor, gamma (IL2RG), a common gamma subunit shared by the receptors of many different cytokines. The ligand binding of this receptor leads to the activation of various JAK kinases and STAT proteins, which connect to different biologic responses. This gene is located at the pseudoautosomal regions of X and Y chromosomes. Genetic studies suggested an association of this gene with the development of asthma. Multiple pseudogenes on chromosome 9, 10, 16, and 18 have been described. Alternatively spliced transcript variants have been found for this gene.
Somiglianze di sequenza
Belongs to the type I cytokine receptor family. Type 4 subfamily.
Posizione cellulare
Cell membrane. Secreted.
