IL3RB è un gene codificato dal simbolo CSF2RB. Comunemente indicato anche come: Cytokine receptor common subunit beta; CDw131; GM-CSF/IL-3/IL-5 receptor common beta subunit; CSF2RB; IL5RB. IL3RB ha una massa di 97.34kDa, una lunghezza di amminoacidi di 897, ed è implicato in Pulmonary surfactant metabolism dysfunction 5.
Offriamo 3 anticorpi contro IL3RB, allevati nel Coniglio, che sono adatti per WB, IHC e ELISA con campioni derivati da Umano, Topo e Ratto.
Informazioni su geni e proteine
Riepilogo UniProt
High affinity receptor for interleukin-3, interleukin-5 and granulocyte-macrophage colony-stimulating factor.
Sommario di Entrez
The protein encoded by this gene is the common beta chain of the high affinity receptor for IL-3, IL-5 and CSF. Defects in this gene have been reported to be associated with protein alveolar proteinosis (PAP).
Coinvolgimento nella malattia
Pulmonary surfactant metabolism dysfunction 5: A rare lung disorder due to impaired surfactant homeostasis. It is characterized by alveolar filling with floccular material that stains positive using the periodic acid-Schiff method and is derived from surfactant phospholipids and protein components. Excessive lipoproteins accumulation in the alveoli results in severe respiratory distress.
Somiglianze di sequenza
Belongs to the type I cytokine receptor family. Type 4 subfamily.
Modifica post-translazionale
May be phosphorylated by LYN.
Posizione cellulare
Membrane.
