HURP è un gene codificato dal simbolo DLGAP5. Comunemente indicato anche come: Disks large-associated protein 5; DAP-5; Discs large homolog 7; Disks large-associated protein DLG7; Hepatoma up-regulated protein; DLGAP5; DLG7; KIAA0008. HURP ha una massa di 95.12kDa e una lunghezza di amminoacidi di 846.
Offriamo 6 anticorpi contro HURP, allevati nel Coniglio, che sono adatti per WB, IHC, ELISA e ICC/IF con campioni derivati da Umano, Topo e Ratto.
Informazioni su geni e proteine
Riepilogo UniProt
Potential cell cycle regulator that may play a role in carcinogenesis of cancer cells. Mitotic phosphoprotein regulated by the ubiquitin-proteasome pathway. Key regulator of adherens junction integrity and differentiation that may be involved in CDH1-mediated adhesion and signaling in epithelial cells.
Specificità del tessuto
Abundantly expressed in fetal liver. Expressed at lower levels in bone marrow, testis, colon, and placenta.
Somiglianze di sequenza
Belongs to the SAPAP family.
Modifica post-translazionale
Ubiquitinated, leading to its degradation.
Posizione cellulare
Nucleus. Cytoplasm. Cytoplasm > Cytoskeleton > Spindle.
Localizes to the spindle in mitotic cells. Colocalizes with CDH1 at sites of cell-cell contact in intestinal epithelial cells.
