HMGN2 è un gene codificato dal simbolo HMGN2. Comunemente indicato anche come: Non-histone chromosomal protein HMG-17; High mobility group nucleosome-binding domain-containing protein 2; HMG17. HMGN2 ha una massa di 9.39kDa e una lunghezza di amminoacidi di 90.
Offriamo 8 anticorpi contro HMGN2, allevati nel Coniglio, che sono adatti per WB, IHC, ELISA e ICC/IF con campioni derivati da Umano, Topo e Ratto.
Informazioni su geni e proteine
Riepilogo UniProt
Binds to the inner side of the nucleosomal DNA thus altering the interaction between the DNA and the histone octamer. May be involved in the process which maintains transcribable genes in a unique chromatin conformation (By similarity).
Sommario di Entrez
The protein encoded by this gene binds nucleosomal DNA and is associated with transcriptionally active chromatin. Along with a similar protein, HMGN1, the encoded protein may help maintain an open chromatin configuration around transcribable genes. The protein has also been found to have antimicrobial activity against bacteria, viruses and fungi.
Somiglianze di sequenza
Belongs to the HMGN family.
Modifica post-translazionale
Phosphorylation favors cytoplasmic localization.
Posizione cellulare
Nucleus. Cytoplasm.
Cytoplasmic enrichment upon phosphorylation.
