hCG beta è un gene codificato dal simbolo CGB3. Comunemente indicato anche come: Choriogonadotropin subunit beta 3; Choriogonadotropin subunit beta; CG-beta; Chorionic gonadotropin chain beta; CGB3; CGB. hCG beta ha una massa di 17.74kDa e una lunghezza di amminoacidi di 165.
Offriamo 43 anticorpi contro hCG beta, allevati nel Coniglio, Topo e Sheep, che sono adatti per WB, IHC, ELISA, ICC/IF, IP e RIA con campioni derivati da Umano, Topo e Ratto.
Informazioni su geni e proteine
Riepilogo UniProt
Beta subunit of the human chorionic gonadotropin (hCG). hCG is a complex glycoprotein composed of two glycosylated subunits alpha and beta which are non-covalently associated. The alpha subunit is identical to those in the pituitary gonadotropin hormones (LH, FSH and TSH). The beta subunits are distinct in each of the hormones and confer receptor and biological specificity. Has an essential role in pregnancy and maternal adaptation. Stimulates the ovaries to synthesize the steroids that are essential for the maintenance of pregnancy.
Sommario di Entrez
This gene is a member of the glycoprotein hormone beta chain family and encodes the beta 3 subunit of chorionic gonadotropin (CG). Glycoprotein hormones are heterodimers consisting of a common alpha subunit and an unique beta subunit which confers biological specificity. CG is produced by the trophoblastic cells of the placenta and stimulates the ovaries to synthesize the steroids that are essential for the maintenance of pregnancy. The beta subunit of CG is encoded by 6 genes which are arranged in tandem and inverted pairs on chromosome 19q13.3 and contiguous with the luteinizing hormone beta subunit gene.
Specificità del tessuto
High expression in the placenta throughout pregnancy.
Somiglianze di sequenza
Belongs to the glycoprotein hormones subunit beta family.
Posizione cellulare
Secreted.
