GRAP2 è un gene codificato dal simbolo GRAP2. Comunemente indicato anche come: GRB2-related adapter protein 2; Adapter protein GRID; GRB-2-like protein; GRB2L; GRBLG; GRBX; Grf40 adapter protein; Grf-40; Growth factor receptor-binding protein; Hematopoietic cell-associated adapter protein GrpL; P38; Protein GADS; SH3-SH2-SH3 adapter Mona; GADS; GRID. GRAP2 ha una massa di 37.91kDa e una lunghezza di amminoacidi di 330.
Offriamo 11 anticorpi contro GRAP2, allevati nel Coniglio, Topo e Capra, che sono adatti per WB, IHC, ELISA, Citometria a Flusso e IP con campioni derivati da Umano, Topo e Ratto.
Informazioni su geni e proteine
Riepilogo UniProt
Interacts with SLP-76 to regulate NF-AT activation. Binds to tyrosine-phosphorylated shc.
Sommario di Entrez
This gene encodes a member of the GRB2/Sem5/Drk family. This member is an adaptor-like protein involved in leukocyte-specific protein-tyrosine kinase signaling. Like its related family member, GRB2-related adaptor protein (GRAP), this protein contains an SH2 domain flanked by two SH3 domains. This protein interacts with other proteins, such as GRB2-associated binding protein 1 (GAB1) and the SLP-76 leukocyte protein (LCP2), through its SH3 domains. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Somiglianze di sequenza
Belongs to the GRB2/sem-5/DRK family.
Posizione cellulare
Nucleus. Cytoplasm. Endosome.
