Anticorpi FLIP

14 prodotti

FLIP è un gene codificato dal simbolo CFLAR. Altri nomi includono: CASP8 and FADD-like apoptosis regulator; Caspase homolog; CASH; Caspase-eight-related protein; Casper; Caspase-like apoptosis regulatory protein; CLARP; Cellular FLICE-like inhibitory protein; c-FADD-like antiapoptotic molecule 1; FLAME-1; Inhibitor of FLICE; I-FLICE; MACH-related inducer of toxicity; MRIT; Usurpin; CFLAR; CASP8AP1. FLIP ha una massa di 55.34kDa e una lunghezza di amminoacidi di 480.

Offriamo 14 anticorpi contro FLIP, allevati nel Coniglio e Topo, che sono adatti per WB, IHC, ELISA, ICC/IF e Citometria a Flusso con campioni derivati ​​da Umano, Topo e Ratto.

Informazioni su geni e proteine

Riepilogo UniProt
Apoptosis regulator protein which may function as a crucial link between cell survival and cell death pathways in mammalian cells. Acts as an inhibitor of TNFRSF6 mediated apoptosis. A proteolytic fragment (p43) is likely retained in the death-inducing signaling complex (DISC) thereby blocking further recruitment and processing of caspase-8 at the complex. Full length and shorter isoforms have been shown either to induce apoptosis or to reduce TNFRSF-triggered apoptosis. Lacks enzymatic (caspase) activity.
Sommario di Entrez
The protein encoded by this gene is a regulator of apoptosis and is structurally similar to caspase-8. However, the encoded protein lacks caspase activity and appears to be itself cleaved into two peptides by caspase-8. Several transcript variants encoding different isoforms have been found for this gene, and partial evidence for several more variants exists.
Specificità del tessuto
Widely expressed. Higher expression in skeletal muscle, pancreas, heart, kidney, placenta, and peripheral blood leukocytes. Also detected in diverse cell lines. Isoform 8 is predominantly expressed in testis and skeletal muscle.
Somiglianze di sequenza
Belongs to the peptidase C14A family.
Modifica post-translazionale
Proteolytically processed by CASP8 generating subunit p43 and p12.
Western Blot - Anti-FLIP Antibody (A14059) - Antibodies.com
(2)
Western Blot - Anti-CFLAR Antibody (C30033) - Antibodies.com
(2)
Visualizza prodotto10µg Dimensione di prova
Segnaposto immagine Antibodies.com - Scopri di più spendendo meno
Visualizza prodotto10µg Dimensione di prova
Segnaposto immagine Antibodies.com - Scopri di più spendendo meno
Segnaposto immagine Antibodies.com - Scopri di più spendendo meno
Segnaposto immagine Antibodies.com - Scopri di più spendendo meno
Visualizza prodotto5µg Dimensione di prova
Western blot - FLIP Antibody from Signalway Antibody (24029) - Antibodies.com
(2)
Western blot - FLIP Antibody from Signalway Antibody (24030) - Antibodies.com
(2)
Anti-FLIP (H204) Antibody from Bioworld Technology (BS2545) - Antibodies.com
(2)
Western blot - FLIP Antibody from Signalway Antibody (24027) - Antibodies.com
(2)
Western blot - FLIP Antibody from Signalway Antibody (24045) - Antibodies.com
(2)
Western blot - CFLAR Antibody from Signalway Antibody (32710) - Antibodies.com
(2)
Western blot - c-FLIP Polyclonal Antibody from Signalway Antibody (41569) - Antibodies.com
FLIP Antibody from Signalway Antibody (35423) - Antibodies.com

Mostra 1-14 di 14 prodotti

Filtri Menù Principale Contattaci 0Check-out
Inizio pagina