Fatty Acid Synthase è un gene codificato dal simbolo FASN. Altri nomi includono: FASN; FAS. Fatty Acid Synthase ha una massa di 273.43kDa e una lunghezza di amminoacidi di 2511.
Offriamo 11 anticorpi contro Fatty Acid Synthase, allevati nel Coniglio, che sono adatti per WB, IHC, ELISA, ICC/IF e IP con campioni derivati da Umano, Topo e Ratto.
Informazioni su geni e proteine
Riepilogo UniProt
Fatty acid synthetase catalyzes the formation of long-chain fatty acids from acetyl-CoA, malonyl-CoA and NADPH. This multifunctional protein has 7 catalytic activities as an acyl carrier protein.
Sommario di Entrez
The enzyme encoded by this gene is a multifunctional protein. Its main function is to catalyze the synthesis of palmitate from acetyl-CoA and malonyl-CoA, in the presence of NADPH, into long-chain saturated fatty acids. In some cancer cell lines, this protein has been found to be fused with estrogen receptor-alpha (ER-alpha), in which the N-terminus of FAS is fused in-frame with the C-terminus of ER-alpha.
Specificità del tessuto
Ubiquitous. Prominent expression in brain, lung, and liver.
Posizione cellulare
Cytoplasm. Melanosome.
Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
