Endo G è un gene codificato dal simbolo ENDOG. Altri nomi includono: Endonuclease G, mitochondrial; ENDOG. Endo G ha una massa di 32.62kDa e una lunghezza di amminoacidi di 297.
Offriamo 11 anticorpi contro Endo G, allevati nel Coniglio e Topo, che sono adatti per WB, IHC e ELISA con campioni derivati da Umano, Topo e Ratto.
Informazioni su geni e proteine
Riepilogo UniProt
Cleaves DNA at double-stranded (DG)n.(DC)n and at single-stranded (DC)n tracts. In addition to deoxyribonuclease activities, also has ribonuclease (RNase) and RNase H activities. Capable of generating the RNA primers required by DNA polymerase gamma to initiate replication of mitochondrial DNA (By similarity).
Sommario di Entrez
The protein encoded by this gene is a nuclear encoded endonuclease that is localized in the mitochondrion. The encoded protein is widely distributed among animals and cleaves DNA at GC tracts. This protein is capable of generating the RNA primers required by DNA polymerase gamma to initiate replication of mitochondrial DNA.
Somiglianze di sequenza
Belongs to the DNA/RNA non-specific endonuclease family.
Posizione cellulare
Mitochondrion.
