DDX6 è un gene codificato dal simbolo DDX6. Altri nomi includono: Probable ATP-dependent RNA helicase ATP-dependent RNA helicase p54; DEAD box protein 6; Oncogene RCK; HLR2; RCK. DDX6 ha una massa di 54.42kDa e una lunghezza di amminoacidi di 483.
Offriamo 9 anticorpi contro DDX6, allevati nel Coniglio e Capra, che sono adatti per WB, IHC, ELISA, ICC/IF, IP e Dot con campioni derivati da Umano, Topo, Ratto e Pollo.
Informazioni su geni e proteine
Riepilogo UniProt
In the process of mRNA degradation, plays a role in mRNA decapping (PubMed:16364915). Blocks autophagy in nutrient-rich conditions by repressing the expression of ATG-related genes through degradation of their transcripts (PubMed:26098573).
Sommario di Entrez
This gene encodes a member of the DEAD box protein family. The protein is an RNA helicase found in P-bodies and stress granules, and functions in translation suppression and mRNA degradation. It is required for microRNA-induced gene silencing. Multiple alternatively spliced variants, encoding the same protein, have been identified.
Specificità del tessuto
Abundantly expressed in most tissues.
Somiglianze di sequenza
Belongs to the DEAD box helicase family. DDX6/DHH1 subfamily.
Modifica post-translazionale
Sumoylated (PubMed:26184334).
Posizione cellulare
Cytoplasm > P-body. Cytoplasm. Nucleus.
Upon cellular stress, relocalizes to stress granules (PubMed:26184334).
