DDAH2 è un gene codificato dal simbolo DDAH2. Altri nomi includono: N(G),N(G)-dimethylarginine dimethylaminohydrolase 2; DDAH-2; DDAHII; Dimethylargininase-2; Protein G6a; S-phase protein; DDAH; G6A; NG30. DDAH2 ha una massa di 29.64kDa e una lunghezza di amminoacidi di 285.
Offriamo 6 anticorpi contro DDAH2, allevati nel Coniglio e Capra, che sono adatti per WB, IHC, ELISA, ICC/IF e Citometria a Flusso con campioni derivati da Umano, Topo e Ratto.
Informazioni su geni e proteine
Riepilogo UniProt
Hydrolyzes N(G),N(G)-dimethyl-L-arginine (ADMA) and N(G)-monomethyl-L-arginine (MMA) which act as inhibitors of NOS. Has therefore a role in the regulation of nitric oxide generation.
Sommario di Entrez
This gene encodes a dimethylarginine dimethylaminohydrolase. The encoded enzyme functions in nitric oxide generation by regulating the cellular concentrations of methylarginines, which in turn inhibit nitric oxide synthase activity. The protein may be localized to the mitochondria. Alternative splicing resulting in multiple transcript variants.
Specificità del tessuto
Detected in heart, placenta, lung, liver, skeletal muscle, kidney and pancreas, and at very low levels in brain.
Somiglianze di sequenza
Belongs to the DDAH family.
Posizione cellulare
Cytoplasm. Mitochondrion.
Translocates from cytosol to mitochondrion upon IL-1beta stimulation in chondrocytes.
