Cyclin G è un gene codificato dal simbolo CCNG1. Altri nomi includono: Cyclin-G1; Cyclin-G; CCNG1; CCNG; CYCG1. Cyclin G ha una massa di 34.07kDa e una lunghezza di amminoacidi di 295.
Offriamo 6 anticorpi contro Cyclin G, allevati nel Coniglio, che sono adatti per WB, IHC, ELISA e ICC/IF con campioni derivati da Umano, Topo e Ratto.
Informazioni su geni e proteine
Riepilogo UniProt
May play a role in growth regulation. Is associated with G2/M phase arrest in response to DNA damage. May be an intermediate by which p53 mediates its role as an inhibitor of cellular proliferation (By similarity).
Sommario di Entrez
The eukaryotic cell cycle is governed by cyclin-dependent protein kinases (CDKs) whose activities are regulated by cyclins and CDK inhibitors. The protein encoded by this gene is a member of the cyclin family and contains the cyclin box. The encoded protein lacks the protein destabilizing (PEST) sequence that is present in other family members. Transcriptional activation of this gene can be induced by tumor protein p53. Two transcript variants encoding the same protein have been identified for this gene.
Specificità del tessuto
High levels in skeletal muscle, ovary, kidney and colon.
Somiglianze di sequenza
Belongs to the cyclin family. Cyclin G subfamily.
Posizione cellulare
Nucleus.
DNA replication foci after DNA damage.
