CPI17 alpha è un gene codificato dal simbolo PPP1R14A. Altri nomi includono: Protein phosphatase 1 regulatory subunit 14A; 17 kDa PKC-potentiated inhibitory protein of PP1; Protein kinase C-potentiated inhibitor protein of 17 kDa; CPI-17; PPP1R14A; CPI17; PPP1INL. CPI17 alpha ha una massa di 16.69kDa e una lunghezza di amminoacidi di 147.
Offriamo 7 anticorpi contro CPI17 alpha, allevati nel Coniglio e Topo, che sono adatti per WB, IHC, ELISA e ICC/IF con campioni derivati da Umano, Topo e Ratto.
Informazioni su geni e proteine
Riepilogo UniProt
Inhibitor of PPP1CA. Has over 1000-fold higher inhibitory activity when phosphorylated, creating a molecular switch for regulating the phosphorylation status of PPP1CA substrates and smooth muscle contraction.
Sommario di Entrez
The protein encoded by this gene belongs to the protein phosphatase 1 (PP1) inhibitor family. This protein is an inhibitor of smooth muscle myosin phosphatase, and has higher inhibitory activity when phosphorylated. Inhibition of myosin phosphatase leads to increased myosin phosphorylation and enhanced smooth muscle contraction. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
Specificità del tessuto
Isoform 1 is detected in aorta and testis. Isoform 2 is detected in aorta.
Somiglianze di sequenza
Belongs to the PP1 inhibitor family.
Posizione cellulare
Cytoplasm.
