Claudin 3 è un gene codificato dal simbolo CLDN3. Altri nomi includono: Claudin-3; Clostridium perfringens enterotoxin receptor 2; CPE-R 2; Rat ventral prostate.1 protein homolog; hRVP1; CLDN3; C7orf1; CPETR2. Claudin 3 ha una massa di 23.32kDa e una lunghezza di amminoacidi di 220.
Offriamo 13 anticorpi contro Claudin 3, allevati nel Coniglio e Topo, che sono adatti per WB, IHC, ELISA e ICC/IF con campioni derivati da Umano, Topo e Ratto.
Informazioni su geni e proteine
Riepilogo UniProt
Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
Sommario di Entrez
Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this intronless gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. It is also a low-affinity receptor for Clostridium perfringens enterotoxin, and shares aa sequence similarity with a putative apoptosis-related protein found in rat.
Somiglianze di sequenza
Belongs to the claudin family.
Posizione cellulare
Cell junction > Tight junction. Cell membrane.
