Chromogranin A è un gene codificato dal simbolo CHGA. Altri nomi includono: Chromogranin-A; CgA; Pituitary secretory protein I; SP-I; CHGA. Chromogranin A ha una massa di 50.69kDa e una lunghezza di amminoacidi di 457.
Offriamo 84 anticorpi contro Chromogranin A, allevati nel Coniglio, Topo, Capra e Sheep, che sono adatti per WB, IHC, ELISA, ICC/IF, Citometria a Flusso e RIA con campioni derivati da Umano, Topo, Ratto, Bovino, Maiale, Scimmia, Cane e Cavallo.
Informazioni su geni e proteine
Riepilogo UniProt
Strongly inhibits glucose induced insulin release from the pancreas.
Sommario di Entrez
The protein encoded by this gene is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. It is found in secretory vesicles of neurons and endocrine cells. This gene product is a precursor to three biologically active peptides; vasostatin, pancreastatin, and parastatin. These peptides act as autocrine or paracrine negative modulators of the neuroendocrine system. Two other peptides, catestatin and chromofungin, have antimicrobial activity and antifungal activity, respectively. Two transcript variants encoding different isoforms have been found for this gene.
Specificità del tessuto
GE-25 is found in the brain.
Somiglianze di sequenza
Belongs to the chromogranin/secretogranin protein family.
Modifica post-translazionale
Sulfated on tyrosine residues and/or contains sulfated glycans.
Posizione cellulare
Secreted. Cytoplasmic vesicle > Secretory vesicle.
Pyroglutaminated serpinin localizes to secretory vesicle.
