CDX2 è un gene codificato dal simbolo CDX2. Altri nomi includono: Homeobox protein CDX-2; CDX-3; Caudal-type homeobox protein 2; CDX3. CDX2 ha una massa di 33.52kDa e una lunghezza di amminoacidi di 313.
Offriamo 47 anticorpi contro CDX2, allevati nel Coniglio, Topo e Capra, che sono adatti per WB, IHC, ELISA, ICC/IF e IP con campioni derivati da Umano, Topo, Ratto e Scimmia.
Informazioni su geni e proteine
Riepilogo UniProt
Involved in the transcriptional regulation of multiple genes expressed in the intestinal epithelium. Important in broad range of functions from early differentiation to maintenance of the intestinal epithelial lining of both the small and large intestine. Binds preferentially to methylated DNA (PubMed:28473536).
Sommario di Entrez
This gene is a member of the caudal-related homeobox transcription factor gene family. The encoded protein is a major regulator of intestine-specific genes involved in cell growth an differentiation. This protein also plays a role in early embryonic development of the intestinal tract. Aberrant expression of this gene is associated with intestinal inflammation and tumorigenesis.
Somiglianze di sequenza
Belongs to the Caudal homeobox family.
Modifica post-translazionale
Phosphorylation of Ser-60 mediates the transactivation capacity.
Posizione cellulare
Nucleus.
