CDA è un gene codificato dal simbolo CDA. Altri nomi includono: Cytidine deaminase; Cytidine aminohydrolase; CDD. CDA ha una massa di 16.19kDa e una lunghezza di amminoacidi di 146.
Offriamo 8 anticorpi contro CDA, allevati nel Coniglio, che sono adatti per WB, IHC e ICC/IF con campioni derivati da Umano, Topo e Ratto.
Informazioni su geni e proteine
Riepilogo UniProt
This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.
Sommario di Entrez
This gene encodes an enzyme involved in pyrimidine salvaging. The encoded protein forms a homotetramer that catalyzes the irreversible hydrolytic deamination of cytidine and deoxycytidine to uridine and deoxyuridine, respectively. It is one of several deaminases responsible for maintaining the cellular pyrimidine pool. Mutations in this gene are associated with decreased sensitivity to the cytosine nucleoside analogue cytosine arabinoside used in the treatment of certain childhood leukemias.
Specificità del tessuto
Highly expressed in granulocytes while expression is very low in fibroblasts, chondrocytes, monocytes, and T- as well as B-cell lines.
Somiglianze di sequenza
Belongs to the cytidine and deoxycytidylate deaminase family.
