CD82 è un gene codificato dal simbolo CD82. Altri nomi includono: CD82 antigen; C33 antigen; IA4; Inducible membrane protein R2; Metastasis suppressor Kangai-1; Suppressor of tumorigenicity 6 protein; Tetraspanin-27; Tspan-27; KAI1; SAR2; ST6; TSPAN27. CD82 ha una massa di 29.63kDa e una lunghezza di amminoacidi di 267.
Offriamo 12 anticorpi contro CD82, allevati nel Coniglio e Topo, che sono adatti per WB, IHC, ICC/IF, Citometria a Flusso e IP con campioni derivati da Umano, Topo e Ratto.
Informazioni su geni e proteine
Riepilogo UniProt
Associates with CD4 or CD8 and delivers costimulatory signals for the TCR/CD3 pathway.
Sommario di Entrez
This metastasis suppressor gene product is a membrane glycoprotein that is a member of the transmembrane 4 superfamily. Expression of this gene has been shown to be downregulated in tumor progression of human cancers and can be activated by p53 through a consensus binding sequence in the promoter. Its expression and that of p53 are strongly correlated, and the loss of expression of these two proteins is associated with poor survival for prostate cancer patients. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Specificità del tessuto
Lymphoid specific.
Somiglianze di sequenza
Belongs to the tetraspanin (TM4SF) family.
Posizione cellulare
Cell membrane.
