CD23 è un gene codificato dal simbolo FCER2. Altri nomi includono: Low affinity immunoglobulin epsilon Fc receptor; BLAST-2; C-type lectin domain family 4 member J; Fc-epsilon-RII; Immunoglobulin E-binding factor; Lymphocyte IgE receptor; FCER2A; CLEC4J; FCE2; IGEBF. CD23 ha una massa di 36.47kDa e una lunghezza di amminoacidi di 321.
Offriamo 52 anticorpi contro CD23, allevati nel Coniglio e Topo, che sono adatti per WB, IHC, ELISA, ICC/IF e Citometria a Flusso con campioni derivati da Umano, Topo e Ratto.
Informazioni su geni e proteine
Riepilogo UniProt
Low-affinity receptor for immunoglobulin E (IgE) and CR2/CD21. Has essential roles in the regulation of IgE production and in the differentiation of B-cells (it is a B-cell-specific antigen).
Sommario di Entrez
The protein encoded by this gene is a B-cell specific antigen, and a low-affinity receptor for IgE. It has essential roles in B cell growth and differentiation, and the regulation of IgE production. This protein also exists as a soluble secreted form, then functioning as a potent mitogenic growth factor. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Modifica post-translazionale
N- and O-glycosylated.
Posizione cellulare
Cell membrane. Cell membrane. Secreted.
Also exists as a soluble excreted form, sCD23.
