Cathepsin H è un gene codificato dal simbolo CTSH. Altri nomi includono: Pro-CTSH; CPSB. Cathepsin H ha una massa di 37.39kDa e una lunghezza di amminoacidi di 335.
Offriamo 7 anticorpi contro Cathepsin H, allevati nel Coniglio e Topo, che sono adatti per WB, IHC e ELISA con campioni derivati da Umano, Topo e Ratto.
Informazioni su geni e proteine
Riepilogo UniProt
Important for the overall degradation of proteins in lysosomes.
Sommario di Entrez
The protein encoded by this gene is a lysosomal cysteine proteinase important in the overall degradation of lysosomal proteins. It is composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. The encoded protein, which belongs to the peptidase C1 protein family, can act both as an aminopeptidase and as an endopeptidase. Increased expression of this gene has been correlated with malignant progression of prostate tumors. Alternate splicing of this gene results in multiple transcript variants encoding different isoforms.
Somiglianze di sequenza
Belongs to the peptidase C1 family.
Posizione cellulare
Lysosome.
