Carbonic Anhydrase III è un gene codificato dal simbolo CA3. Altri nomi includono: Carbonic anhydrase 3; Carbonate dehydratase III; CA-III; CA3. Carbonic Anhydrase III ha una massa di 29.56kDa e una lunghezza di amminoacidi di 260.
Offriamo 6 anticorpi contro Carbonic Anhydrase III, allevati nel Coniglio, che sono adatti per WB, IHC, ELISA e ICC/IF con campioni derivati da Umano, Topo e Ratto.
Informazioni su geni e proteine
Riepilogo UniProt
Reversible hydration of carbon dioxide.
Sommario di Entrez
Carbonic anhydrase III (CAIII) is a member of a multigene family (at least six separate genes are known) that encodes carbonic anhydrase isozymes. These carbonic anhydrases are a class of metalloenzymes that catalyze the reversible hydration of carbon dioxide and are differentially expressed in a number of cell types. The expression of the CA3 gene is strictly tissue specific and present at high levels in skeletal muscle and much lower levels in cardiac and smooth muscle. A proportion of carriers of Duchenne muscle dystrophy have a higher CA3 level than normal. The gene spans 10.3 kb and contains seven exons and six introns.
Specificità del tessuto
Muscle specific.
Somiglianze di sequenza
Belongs to the alpha-carbonic anhydrase family.
Modifica post-translazionale
S-glutathionylated in hepatocytes under oxidative stress.
Posizione cellulare
Cytoplasm.
